Donepezil hydrochloride
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370 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Alzheimer disease | D000544 | EFO_0000249 | F03 | 37 | 50 | 32 | 39 | 46 | 199 |
| Dementia | D003704 | EFO_0003862 | F03 | 5 | 9 | 16 | 11 | 15 | 55 |
| Cognitive dysfunction | D060825 | — | G31.84 | 8 | 13 | 7 | 8 | 9 | 44 |
| Parkinson disease | D010300 | EFO_0002508 | G20 | 1 | 5 | 3 | 5 | 3 | 17 |
| Stroke | D020521 | EFO_0000712 | I63.9 | 2 | 2 | 3 | 3 | 2 | 11 |
| Cognition disorders | D003072 | — | — | 1 | 4 | — | 3 | 2 | 9 |
| Lewy body disease | D020961 | EFO_0006792 | G31.83 | — | 2 | 1 | 2 | 4 | 9 |
| Memory disorders | D008569 | — | — | 2 | 1 | 2 | 1 | 2 | 8 |
| Depression | D003863 | — | F33.9 | — | 2 | 2 | 2 | — | 6 |
| Vascular dementia | D015140 | — | F01 | 1 | — | 3 | 1 | 1 | 6 |
Show 41 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Syndrome | D013577 | — | — | 1 | 4 | 4 | — | 1 | 10 |
| Down syndrome | D004314 | EFO_0001064 | Q90 | — | 3 | 2 | — | — | 5 |
| Mixed dementias | D000093902 | — | — | — | — | 1 | — | 2 | 3 |
| Radiation effects | D011830 | — | — | 1 | 1 | 1 | — | — | 3 |
| Rett syndrome | D015518 | Orphanet_778 | F84.2 | — | — | 1 | — | 1 | 2 |
| Anxiety disorders | D001008 | EFO_0006788 | F41.1 | — | 1 | 1 | — | — | 2 |
| Brain injuries | D001930 | — | S06.9 | 1 | 1 | 1 | — | — | 2 |
| Alcoholism | D000437 | EFO_0003829 | F10.1 | — | 2 | 1 | — | — | 2 |
| Ischemic stroke | D000083242 | — | — | — | 1 | 1 | — | — | 2 |
| Neoplasms | D009369 | — | C80 | 1 | — | 1 | — | — | 2 |
Show 13 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Cocaine-related disorders | D019970 | — | F14 | — | 3 | — | — | — | 3 |
| Central nervous system neoplasms | D016543 | — | — | 2 | 1 | — | — | — | 3 |
| Autism spectrum disorder | D000067877 | — | F84.0 | — | 2 | — | — | — | 2 |
| Fragile x syndrome | D005600 | — | Q99.2 | 1 | 1 | — | — | — | 2 |
| Nervous system neoplasms | D009423 | — | — | 1 | 1 | — | — | — | 2 |
| Anorexia | D000855 | — | R63.0 | — | 2 | — | — | — | 2 |
| Anorexia nervosa | D000856 | EFO_0004215 | F50.0 | — | 2 | — | — | — | 2 |
| Consciousness disorders | D003244 | — | — | 1 | 1 | — | — | — | 1 |
| Pervasive child development disorders | D002659 | EFO_0003756 | F84 | — | 1 | — | — | — | 1 |
| Type 2 diabetes mellitus | D003924 | EFO_0001360 | E11 | — | 1 | — | — | — | 1 |
Show 20 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | — | — | 31 | — | — | — | 1 | 32 |
| Nervous system diseases | D009422 | — | G00-G99 | 2 | — | — | — | 2 | 4 |
| Central nervous system diseases | D002493 | — | G96.9 | 2 | — | — | — | 1 | 3 |
| Malnutrition | D044342 | EFO_0008572 | E40-E46 | 3 | — | — | — | — | 3 |
| Crush injuries | D000071576 | — | T14.8 | 1 | — | — | — | — | 1 |
| Pain | D010146 | EFO_0003843 | R52 | 1 | — | — | — | — | 1 |
| Nerve degeneration | D009410 | — | — | 1 | — | — | — | — | 1 |
| Hyperalgesia | D006930 | — | — | 1 | — | — | — | — | 1 |
| Rh isoimmunization | D012203 | EFO_1001159 | — | 1 | — | — | — | — | 1 |
| Neurotoxicity syndromes | D020258 | — | G92 | 1 | — | — | — | — | 1 |
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Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy aging | D000073656 | — | — | — | — | — | — | 2 | 2 |
| Brain diseases | D001927 | — | G93.40 | — | — | — | — | 2 | 2 |
| Neurodegenerative diseases | D019636 | EFO_0005772 | G31.9 | — | — | — | — | 2 | 2 |
| Late onset disorders | D000067562 | — | — | — | — | — | — | 1 | 1 |
| Tauopathies | D024801 | — | — | — | — | — | — | 1 | 1 |
| Hypercholesterolemia | D006937 | — | — | — | — | — | — | 1 | 1 |
| Gait | D005684 | — | — | — | — | — | — | 1 | 1 |
| Diabetes mellitus | D003920 | EFO_0000400 | E08-E13 | — | — | — | — | 1 | 1 |
| Gastrointestinal motility | D005769 | — | — | — | — | — | — | 1 | 1 |
| Hypertension | D006973 | EFO_0000537 | I10 | — | — | — | — | 1 | 1 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Adverse Events
Top Adverse Reactions
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2,012 adverse events reported
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